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However, TGF- signaling can suppress AhR expression via methyl-CpG-binding domain 2 (MBD2) -mediated promoter methylation, potentially limiting the antifibrotic efficacy of Kyn [117]
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The authors of the study collected urine and blood specimens from the participants and performed MRS scans on their brains prior to the first dose of sulforaphane and within four hours of the final dose
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